EFFECT OF CONTINUOUS ENVIRONMENTAL ENRICHMENT AND AEROBIC EXERCISE ON RAT PLASMA AND HIPPOCAMPAL BRAIN‑DERIVED NEUROTROPHIC FACTOR

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UEU » Journal » Fisioterapi
Posted by [email protected] at 04/08/2021 13:42:24 • 450 Views

EFFECT OF CONTINUOUS ENVIRONMENTAL ENRICHMENT AND AEROBIC EXERCISE ON RAT PLASMA AND HIPPOCAMPAL BRAIN‑DERIVED NEUROTROPHIC FACTOR

Pengaruh Pengayaan Lingkungan Berkelanjutan dan Latihan Aerobik pada Plasma Tikus dan Otak Hipokampus Faktor Neurotropik yang Diturunkan

Created by :
Sri Redjeki Prasetyo ( None )
Sophie Yolanda; Kesit Ivanali

Subject:	OLAHRAGA AEROBIK PLASMA TIKUS
Alt. Subject :	SPORT AEROBIC RATS PLASMA
Keyword:	Aerobic exercise brain‑ derived neurotrophic factor environmental enrichment hippocampus

Description:

Objective: Environmental enrichment (EE) or exercise can positively affect memory function through increased long‑term potentiation and neurogenesis, which is facilitated by brain‑derived neurotrophic factor (BDNF). BDNF promotes blood vessel growth, angiogenesis linked to adult neurogenesis, and neuronal survival. Here, we investigated the effects of EE, aerobic exercise, and their combination on plasma and hippocampal BDNF levels. Materials and Methods: Twenty‑four 7‑month‑old adult male Wistar rats weighing 300�400 g were randomly assigned to the following four groups: control (C), aerobic exercise (A), EE, and combined EE and aerobic exercise (EEA). Interventions were given for 8 weeks, and plasma and hippocampal BDNF levels were measured using enzyme‑linked immunosorbent assay. Results: A combination of aerobic exercise and continuous EE produced the largest increase in hippocampal and plasma BDNF levels in adult rats. A positive correlation (r = 0.686, P = 0.002, n = 24) was observed between plasma and hippocampal BDNF levels in adult rats. Conclusion: We conclude that a combination of aerobic exercise and continuous EE increases plasma and hippocampal BDNF in adult rats.

Date Create	:	04/08/2021
Type	:	Text
Format	:	pdf
Language	:	Indonesian
Identifier	:	UEU-Journal-11_1808
Collection ID	:	11_1808

Source :
Journal of Natural Science, Biology and Medicine Volume 10 Supplement 1 November 2019

Relation Collection:
Fakultas Fisioterapi

Coverage :
Civitas Akademika Universitas Esa Unggul

Rights :
@2021 Perpustakaan Universitas Esa Unggul

Publication URL :
https://digilib.esaunggul.ac.id/effect-of-continuous-environmental-enrichment-and-aerobic-exercise-on-rat-plasma-and-hippocampal-brain8209derived-neurotrophic-factor-21043.html

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