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UEU » Journal » Farmasi Posted by [email protected] at 23/12/2022 14:09:52 • 685 Views
IN VITRO ASSAY OF ACE INHIBITOR, ANTIDIABETIC AND ANTIOXIDANTS ACTIVITIES FROM INDONESIA TRADITIONAL MEDICINE (JAMU)Created by :
Aprilita Rina Yanti Eff ( 0318046802 ) Reza Ayu Pertiwi, Annisah Nurziah Sujadi, Maharani Hestu Muktiwisesa
Subject: | OBAT TRADISIONAL JAMU | Alt. Subject : | HERBAL MEDICINE STANDARDIZATION ANTIHYPERTENSIVE ANTIDIABETIC ANTIOXIDANT. | Keyword: | ANTI OKSIDAN ANTI DIABETES ANTI HIPERTENSI |
Alt. Description
Hypertension in people with diabetes causes accelerated complications of the heart and kidneys. Angiotensin Converting Enzyme (ACE)
inhibitors are the first choice managing of hypertension in patients with diabetes mellitus. Herbal medicine is a native Indonesian treatment
that has been used since time immemorial to overcome various diseases, including hypertension and diabetes mellitus. This study aims to
standardize and assay the in vitro ACE inhibitor, antidiabetic, and antioxidant activities on Indonesian medicinal plants (jamu). Methods:
Jamu was extracted by maceration using ethanol. Standardization includes non-specific and specific parameters. The activity of
angiotensin-converting enzyme inhibitor, alpha-glucosidase enzyme inhibiting activity, and antioxidant activity using a spectrophotometer.
The results showed that jamu met the requirements of both specific and non-specific parameters, had angiotensin-converting enzyme
inhibitors, alpha-glucosidase enzyme inhibitors, and antioxidants activity with IC50 values 103.75 �g/ml, 49.95 �g/ml, and 11.4 �g/ml.
Conclusion: jamu meets the requirements according to the Indonesian Herbal Pharmacopoeia standards and has antihypertensive,
antidiabetic, and antioxidant activities.
Date Create | : | 23/12/2022 | Type | : | Text | Format | : | pdf | Language | : | Indonesian | Identifier | : | UEU-Journal-11_3556 | Collection ID | : | 11_3556 |
Source : Research Journal of Pharmacy and Technology. 2022; 15(9):4212-7
Relation Collection: Fakultas Ilmu-Ilmu Kesehatan
Coverage : Civitas Akademika Universitas Esa Unggul
Rights : @2022 Perpustakaan Universitas Esa Unggul
Publication URL : https://digilib.esaunggul.ac.id/in-vitro-assay-of-ace-inhibitor-antidiabetic-and-antioxidants-activities-from-indonesia-traditional-medicine-jamu-27005.html
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