THE ROLE OF PDGF GENE IN TISSUE REGENERATION OF DIGIT TIP MICE (MUS MUSCULUS)

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UEU » Proceeding » Bioteknologi
Posted by [email protected] at 01/09/2021 10:56:44 • 507 Views

THE ROLE OF PDGF GENE IN TISSUE REGENERATION OF DIGIT TIP MICE (MUS MUSCULUS)

Peran Gen PDGF dalam Regenerasi Jaringan Tikus Ujung Jari (Mus musculus)

Created by :
Titta Novianti ( 0318116801 )
Tazkia Ayu Safitri; Febriana Dwi Wahyuni; It Jamilah; Syafruddin Ilyas

Subject:	PERTUMBUHAN REGENERASI TIKUS
Alt. Subject :	GROWTH REGENERATION MOUSE
Keyword:	PDGF tissue regeneration mice granule phase amputated

Description:

Some genes play a role in the tissue regeneration process and they have specific functions. One of them is the platelet-derived growth factors (PDGF) gene that have a role in the wound healing process because it induces cell mitosis and thereby causes cell proliferation. PDGF protein expression is thought to chemotactically recruit many cell types including smooth muscle, fibroblasts, and monocytes to migrate to the wound site. These research aims are to analyze the role of PDGF gene expression in the process of digit tip mice tissue regeneration. This study used 24 mice (Mus musculus) were amputated at the digit tip and the growth was observed on days 0, 1, 3, 5, 10, 15, and 25. We isolated RNA from each tissue after amputation on days 0, 1, 3, 5, 10, 15, and 25 and analyzed the RNA expression of the PDGF gene using the qPCR method. PDGF gene expression reached its peak on day 10 on the granule phase and decreased until day 25. The peak expression of the PDGF gene indicates the role of the gene in the tissue regeneration of digit tip mice. The normality test for PDGF gene expression was normally distributed (p> 0, 05) and the variation test between each treatment was different significantly (p <0.05).

Date Create	:	01/09/2021
Type	:	Text
Format	:	pdf
Language	:	Indonesian
Identifier	:	UEU-Proceeding-14_0076
Collection ID	:	14_0076

Source :
Proceedings of the 3rd KOBI Congress, International and National Conferences (KOBICINC 2020)

Relation Collection:
Fakultas Ilmu-Ilmu Kesehatan

Coverage :
Civitas Akademika Universitas Esa Unggul

Rights :
@2021 Perpustakaan Universitas Esa Unggul

Publication URL :
https://digilib.esaunggul.ac.id/the-role-of-pdgf-gene-in-tissue-regeneration-of-digit-tip-mice-mus-musculus-21563.html

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