SARS-COV-2: VIROLOGI DAN TARGET OBAT

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UEU » Journal » Farmasi
Posted by [email protected] at 15/08/2021 00:49:44 • 559 Views

SARS-COV-2: VIROLOGI DAN TARGET OBAT

SARS-Cov-2: Virology and Drug Targets

Created by :
Aprilita Rina Yanti Eff ( 0318046802 )

Subject:	PANDEMI OBAT COVID-19
Alt. Subject :	PANDEMIC DRUG CORONAVIRUS
Keyword:	SARS-COV-2 ANTIVIRUS

Description:

Pandemi COVID-19 yang disebabkan oleh coronavirus 2 (SARS-CoV-2) menimbulkan tantangan bagi para peneliti dalam mengidentifikasi obat yang efektif untuk pencegahan maupun pengobatan Covid-19. Pengetahuan yang berkembang pesat mengenai virologi SARS-CoV-2 memberikan informasi sejumlah besar target obat yang potensial. Banyak terapi telah dilaporkan efektif menghambat replikasi SARS-CoV-2 sejak merebaknya pandemi ini. Target utama pada obat-obat ini adalah protein esensial dalam siklus hidup virus. Beberapa obat saat ini direkomendasikan untuk pasien COVID-19 yang memiliki gejala sedang hingga berat, termasuk obat antivirus Favipiravir, Remdesivir, Baricitinib dan Kortikosteroid. Pendekatan saat ini untuk terapi COVID-19 umumnya terbagi dalam dua kategori: antivirus yang mencegah virus bereplikasi dan imunomodulator yang membantu sistem kekebalan untuk melawan virus. Pandemi Covid-19 merupakan tantangan dan krisis kesehatan global. Oleh karena itu sangat dibutuhkan kecepatan dan jumlah uji klinis obat-obat yang potensial untuk Covid-19. Sampai saat ini belum ada terapi yang terbukti efektif dalam mengobati covid-19.

Alt. Description

COVID-19 pandemic caused by coronavirus 2 (SARS-CoV-2) poses challenges for researchers in identifying effective drugs for the prevention and treatment of COVID-19. The rapidly growing knowledge of the virology of SARS-CoV-2 provides large number of potential drug targets information. Many therapies have been reported to be effective at inhibiting SARS-CoV-2 replication since the outbreak of this pandemic. The main targets of these drugs are proteins essential in the viral life cycle. Several medications are currently recommended for COVID-19 patients with moderate to severe symptoms, including the antiviral drugs favipiravir, remdesivir, baricitinib, and corticosteroids. Current approaches to COVID-19 therapy generally fall into two categories: antivirals that prevent the virus from replicating and immunomodulators that help the immune system fight the virus. The Covid-19 pandemic is a global health challenge and crisis. Therefore, the speed and number of clinical trials of potential drugs for Covid-19 are urgently needed. So far, no therapy is effective in treating COVID-19.

Date Create	:	15/08/2021
Type	:	Text
Format	:	pdf
Language	:	Indonesian
Identifier	:	UEU-Journal-11_1821
Collection ID	:	11_1821

Source :
Archives Pharmacia Volume 3 Nomor 2, Juli 2021

Relation Collection:
Civitas Akademika Universitas Esa Unggul

Coverage :
Fakultas Ilmu-Ilmu Kesehatan

Rights :
@2021 Perpustakaan Universitas Esa Unggul

Publication URL :
https://digilib.esaunggul.ac.id/sarscov2-virologi-dan-target-obat-21129.html

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