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UEU » Proceeding » Farmasi
Posted by [email protected] at 22/04/2022 10:03:13  •  156 Views


IN-VITRO Α-GLUCOSIDASE INHIBITORY ACTIVITY OF LITSEA PETIOLATA HK. F

Created by :
Neneng Siti Silfi Ambarwati ( none )
Berna Elya2; Putu Gita Maya Widyaswari Mahayasih (0318089202); Muhamad Sharul Nizam Awang; Hanita Omar; Islamudin Ahmad; Dwi Atmanto



SubjectENZIM
OBAT SINTETIK
OBAT-OBATAN ALAMI
Alt. Subject ENZYME
SYNTHETIC DRUGS
NATURAL MEDICINE
KeywordLitsea petiolata Hk. F
extract
fraction
alpha-glucosidase inhibitory

Description:

Alpha-glucosidase is an enzyme that plays a role in the process of hydrolysis of carbohydrates into glucose so that the enzyme inhibitor can inhibit the process of glucose absorption. One synthetic drug that has a mechanism of action to inhibit the activity of the alpha-glucosidase enzyme is acarbose, however in the long term has side effects, such as digestive system disorders. Therefore, the use of natural medicines as alternative therapies can be considered for use. This study aimed to determine the inhibitory activity of the enzyme alpha-glucosidase from extracts and fractions of Litsea petiolata Hk. f bark. The extraction method used maceration, and fractionation using column chromatography. The results showed that the IC50 values for extract, fraction B, fraction D, and acarbose were 444.17 μg/ml, 682.85 μg/ml, 1683.45 μg/ml, and 110.60 μg/ml, respectively. In conclusion, the activity extract as the alpha-glucosidase was higher than the fractions but lower than acarbose.

Date Create:22/04/2022
Type:Text
Format:pdf
Language:English
Identifier:UEU-Proceeding-14_0259
Collection ID:14_0259


Source :
Proceedings of the 1st International Conference on Health Science, ICHS 2020, 26-27 October 2020, Jakarta, Indonesia

Relation Collection:
Fakultas Ilmu-ilmu Kesehatan

Coverage :
Civitas Akademika Universitas Esa Unggul

Rights :
@2022 Perpustakaan Universitas Esa Unggul


Publication URL :
https://digilib.esaunggul.ac.id/invitro-913glucosidase-inhibitory-activity-of-litsea-petiolata-hk-f-24865.html




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[ Link of Contents]
  1. IN-VITRO Α-GLUCOSIDASE INHIBITORY ACTIVITY OF LITSEA PETIOLATA HK. F
    https://eudl.eu/doi/10.4108/eai.26-10-2020.2311312

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F , Hk. , Litsea , Litsea petiolata Hk. F , alpha-glucosidase , alpha-glucosidase inhibitory , extract , fraction , inhibitory , petiolata



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