CARRIAGE OF STREPTOCOCCUS PNEUMONIAE IN CHILDREN UNDER FIVE YEARS OF AGE PRIOR TO PNEUMOCOCCAL VACCINE INTRODUCTION IN SOUTHEAST ASIA: A SYSTEMATIC REVIEW AND META-ANALYSIS (2001-2019)

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UEU » Journal » Kesehatan Masyarakat
Posted by [email protected] at 22/09/2021 15:11:20 • 404 Views

CARRIAGE OF STREPTOCOCCUS PNEUMONIAE IN CHILDREN UNDER FIVE YEARS OF AGE PRIOR TO PNEUMOCOCCAL VACCINE INTRODUCTION IN SOUTHEAST ASIA: A SYSTEMATIC REVIEW AND META-ANALYSIS (2001-2019)

Pengangkutan Streptococcus pneumoniae pada anak di bawah usia lima tahun sebelum pengenalan vaksin pneumokokus di Asia Tenggara: Tinjauan sistematis dan meta-analisis (2001-2019)

Created by :
Wa Ode Dwi Daningrat ( None )
Hafsah Amalia; Ira Marti Ayu; Catherine Satzke; Dodi Safari

Subject:	INFEKSI PARU-PARU VAKSIN ANAK
Alt. Subject :	LUNG INFECTION VACCINE CHILD
Keyword:	Streptococcus pneumoniae carriage Pneumococcal conjugate vaccine Southeast Asia

Description:

A number of pneumococcal carriage studies in children have been conducted in recent years. However, summary data of carriage prevalence and serotype distribution from South East Asia Region (SEAR) are limited. This may lead to the misconception that Streptococcus pneumoniae vaccine-types are uncommon in the region. Systematic reviews of pneumococcal carriage and the distribution of serotypes are critically important for evidence-based decision-making. We aimed to summarize published data on the serotype prevalence of S. pneumoniae carried in the nasopharynx of children under 5 years of age in SEAR. We performed a systematic review and meta-analysis for relevant studies on S. pneumoniae carriage conducted prior to PCV program implementation from online journal databases published between January 2001 to December 2019. The pooled prevalence of S. pneumoniae in healthy children under 5 years of age in SEAR was 36.0% (95% CI 34.2%e37.8%), and ranged from 68.0% (95% CI: 61.9%e74.0%) in Cambodia to 7.6% (95% CI: 5.7%e9.6%) in Malaysia. Serotypes 6A/B, 23F and 19F were the most common serotypes in children <5 years, accounting for 12.9% (95% CI: 9.4%e16.3%), 9.3% (95% CI: 5.9%e12.8%) and 10.1% (95% CI: 6.6%e13.5%) of isolates, respectively. Vaccine policy makers should take these results into account when making decisions on pneumococcal conjugate vaccine programs implementation. Given the paucity of data, collection of more extensive and updated information of S. pneumoniae serotype epidemiology in children under five years in SEAR is also very important for future studies. Copyright � 2021, Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/bync- nd/4.0/).

Date Create	:	22/09/2021
Type	:	Text
Format	:	pdf
Language	:	Indonesian
Identifier	:	UEU-Journal-11_1853
Collection ID	:	11_1853

Source :
Journal of Microbiology, Immunology and Infection, August 2021

Relation Collection:
Fakultas Ilmu-Ilmu Kesehatan

Coverage :
Civitas Akademika Universitas Esa Unggul

Rights :
@2021 Perpustakaan Universitas Esa Unggul

Publication URL :
https://digilib.esaunggul.ac.id/carriage-of-streptococcus-pneumoniae-in-children-under-five-years-of-age-prior-to-pneumococcal-vaccine-introduction-in-southeast-asia-a-systematic-review-and-metaanalysis-20012019-21950.html

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