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UEU » Research Report » Kesehatan Masyarakat
Posted by [email protected] at 31/10/2016 15:43:49  •  538 Views


MERANCANG MOLEKUL, MEMPELAJARI STRUKTUR, DAN INTERAKSI MOLEKUL YANG BERPOTENSI SEBAGAI EPIGENETIK INHIBITOR IN SILICO

Created by :
Eddy Purwoto B, S.Si, M.Farm ( 215010577 )



SubjectMOLEKUL
EPIGENETIK
KANKER
Alt. Subject MOLECULE
EPIGENETIC
CANCER
Keywordhdaci
n
n dietil sinamamid
docking

Description:

Latar Belakang: Prevalensi Kanker servix di negara berkembang cukup tinggi, sehingga diperlukan obat untuk mengurangi resiko. Kanker servix memiliki interaksi dengan epigenetik. Di Indonesia memiliki diversiti molekul yang beragam. Molekul bahan alam dapat digunakan untuk mencegah kanker servik dan epigenetik. Penapisan in silico molekul diperlukan supaya zat aktif dapat diketahui aktivitasnya dengan cepat dan murah.. Tujuan : Penapisan senyawa dietil sinamamide terhadap HDAC II Metode dan Hasil Penelitian: Molekul dilakukan virtual docking pada HDAC2 dengan pembanding LLX[N-(2-aminophenyl) benzamide]. Kesimpulan: Molekul yang terbentuk N, N dietil sinamamit memiliki aktivitas menghambat HDAC II.

Date Create:31/10/2016
Type:Text
Format:PDF
Language:Indonesian
Identifier:UEU-Research-215010577_260615
Collection ID:215010577_260615


Source :
LAPORAN PENELITIAN HIBAH INTERNAL

Relation Collection:
Fakultas Ilmu Kesehatan

Coverage :
Civitas Akademika Universitas Esa Unggul

Rights :
@2015 LPPM


Publication URL :
https://digilib.esaunggul.ac.id/merancang-molekul-mempelajari-struktur-dan-interaksi-molekul-yang-berpotensi-sebagai-epigenetik-inhibitor-in-silico-7917.html




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