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UEU » Research Report » Kesehatan Masyarakat Posted by [email protected] at 31/10/2016 15:43:49 • 538 Views
MERANCANG MOLEKUL, MEMPELAJARI STRUKTUR, DAN INTERAKSI MOLEKUL YANG BERPOTENSI SEBAGAI EPIGENETIK INHIBITOR IN SILICOCreated by :
Eddy Purwoto B, S.Si, M.Farm ( 215010577 )
Subject: | MOLEKUL EPIGENETIK KANKER | Alt. Subject : | MOLECULE EPIGENETIC CANCER | Keyword: | hdaci n n dietil sinamamid docking |
Description:
Latar Belakang: Prevalensi Kanker servix di negara berkembang cukup tinggi, sehingga diperlukan obat untuk mengurangi resiko. Kanker servix memiliki interaksi dengan epigenetik. Di Indonesia memiliki diversiti molekul yang beragam. Molekul bahan alam dapat digunakan untuk mencegah kanker servik dan epigenetik. Penapisan in silico molekul diperlukan supaya zat aktif dapat diketahui aktivitasnya dengan cepat dan murah..
Tujuan : Penapisan senyawa dietil sinamamide terhadap HDAC II
Metode dan Hasil Penelitian: Molekul dilakukan virtual docking pada HDAC2 dengan pembanding LLX[N-(2-aminophenyl) benzamide].
Kesimpulan: Molekul yang terbentuk N, N dietil sinamamit memiliki aktivitas menghambat HDAC II.
Date Create | : | 31/10/2016 | Type | : | Text | Format | : | PDF | Language | : | Indonesian | Identifier | : | UEU-Research-215010577_260615 | Collection ID | : | 215010577_260615 |
Source : LAPORAN PENELITIAN HIBAH INTERNAL
Relation Collection: Fakultas Ilmu Kesehatan
Coverage : Civitas Akademika Universitas Esa Unggul
Rights : @2015 LPPM
Publication URL : https://digilib.esaunggul.ac.id/merancang-molekul-mempelajari-struktur-dan-interaksi-molekul-yang-berpotensi-sebagai-epigenetik-inhibitor-in-silico-7917.html
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