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UEU » Journal » Farmasi
Posted by [email protected] at 12/01/2021 16:33:46  •  836 Views


AKTIFITAS ANTIBAKTERI EKSTRAK ETANOL KALIKS BUNGA ROSELLA MERAH (HIBISCUS SABDARIFFA L.) TERHADAP MYCOBACTERIUM TUBERCULOSIS

Created by :
Ayu Puspita Lena ( none )
Eddy Purwoto B   Putu Gita Maya WM



SubjectETANOL
ANTIBAKTERI
Alt. Subject ROSELLA
ANTIBACTERIAL
KeywordEKSTRAK
ETANOL

Description:

Rosella merah (Hibiscus sabdariffa L.) merupakan salah satu tanaman obat yang secara empiris telah digunakan sebagai obat antituberkulosis. Kaliks bunga Rosella mengandung antosianin serta berbagai zat gizi lain seperti kalsium, niasin, riboflavin dan zat besi.Penelitian ini bertujuan untuk mengetahui aktivitas ekstrak etanol 70% kaliks bunga rosella (Hibiscus sabdariffa L.) terhadap Mycobacterium tuberculosis strain H Rv. Penelitian dilakukan secara eksperimental diawali dengan pembuatan ekstrak bunga Rosella secara maserasi dilanjutkan dengan penapisan kandungan kimia ekstrak. Efek antibakteri dilakukan secara in-vitro menggunakan 6 kelompok perlakuan, yaitu kelompok kontrol negatif, berisi media dan aquadest, kelompok kontrol pelarut, berisi media dan etanol 70%, kelompok kontrol positif, berisi media dan isoniazid, dan tiga kelompok ekstrak masing-masing berisi media dan ekstrak dengan konsentrasi 2,5 mg/mL, 5 mg/mL dan 10 mg/mL. Suspensi Mycobacterium tuberculosis dituangkan ke seluruh permukaan media diamati pertumbuhannya setelah diinkubasi selama 21 hari. Hasil penelitian menunjukkan ekstrak etanol kaliks bunga Rosella mengandung minyak atsiri, minyak lemak, tannin, gula pereduksi, flavonoid, kumarin, triterpenoid, dan antosianin. Ekstrak etanol 70% kaliks bunga Rosella (Hibiscus sabdariffa L.) pada konsentrasi 10% memiliki efek antibakteri terhadap Mycobacterium tuberculosisdengan menghambat pertumbuhan Mycobacterium tuberculosis mulai dari mingu pertama sampai mnggu ketiga pengamatan.


Alt. Description

The red Rosella (Hibiscus sabdariffa L.) is medicinal plant that empirically has been used as an antituberculous drug. Rosella�s calix contains anthocyanins and other nutrients such as calcium, niacin, riboflavin and iron. This study was conducted experimentally starting with the making of Rosella flower extract by maceration method followed by examination of chemical content of extract. The antibacterial effect was performed by in-vitro method using 6 treatment groups, the negative control group, containing media and aquadest, the ethanol control group, containing media and 70% ethanol, the positive control group, containing media and isoniazid, and three groups of extracts each containing media and extracts with a concentration of 2.5 mg / mL , 5 mg / mL and 10 mg / mL. Mycobacterium tuberculosissuspension was shed over the entire surface and thenthe growth of Mycobacterium tuberculosis was observed after incubated for 21 days. The results showed that the ethanol extract of Rosella flower contain essential oils, fatty oil, tannins, reducing sugars, flavonoids, coumarins, triterpenoids, and anthocyanins. The 70% ethanol extract of calixs of Rosella flower (Hibiscus sabdariffa L.) at a concentration of 10mg/mLpossessinhibit the growth of Mycobacterium tuberculosis from the first week until the third week observation.

Date Create:12/01/2021
Type:Text
Format:pdf
Language:Indonesian
Identifier:UEU-Journal-11_0399
Collection ID:11_0399


Source :
Jurnal Archives Pharmacia Volume 1 Nomor 1, Januari 2019

Relation Collection:
Fakultas Ilmu-Ilmu Kesehatan

Coverage :
Civitas Akademika Universitas Esa Unggul

Rights :
@2021 Perpustakaan Universitas Esa Unggul


Publication URL :
https://digilib.esaunggul.ac.id/aktifitas-antibakteri-ekstrak-etanol-kaliks-bunga-rosella-merah-hibiscus-sabdariffa-l-terhadap-mycobacterium-tuberculosis-17816.html




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