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UEU » Journal » Farmasi Posted by [email protected] at 12/01/2021 16:33:46 • 835 Views
AKTIFITAS ANTIBAKTERI EKSTRAK ETANOL KALIKS BUNGA ROSELLA MERAH (HIBISCUS SABDARIFFA L.) TERHADAP MYCOBACTERIUM TUBERCULOSISCreated by :
Ayu Puspita Lena ( none ) Eddy Purwoto B Putu Gita Maya WM
Subject: | ETANOL ANTIBAKTERI | Alt. Subject : | ROSELLA ANTIBACTERIAL | Keyword: | EKSTRAK ETANOL |
Description:
Rosella merah (Hibiscus sabdariffa L.) merupakan salah satu tanaman obat yang secara empiris telah
digunakan sebagai obat antituberkulosis. Kaliks bunga Rosella mengandung antosianin serta berbagai
zat gizi lain seperti kalsium, niasin, riboflavin dan zat besi.Penelitian ini bertujuan untuk mengetahui
aktivitas ekstrak etanol 70% kaliks bunga rosella (Hibiscus sabdariffa L.) terhadap Mycobacterium
tuberculosis strain H
Rv. Penelitian dilakukan secara eksperimental diawali dengan pembuatan
ekstrak bunga Rosella secara maserasi dilanjutkan dengan penapisan kandungan kimia ekstrak. Efek
antibakteri dilakukan secara in-vitro menggunakan 6 kelompok perlakuan, yaitu kelompok kontrol
negatif, berisi media dan aquadest, kelompok kontrol pelarut, berisi media dan etanol 70%, kelompok
kontrol positif, berisi media dan isoniazid, dan tiga kelompok ekstrak masing-masing berisi media dan
ekstrak dengan konsentrasi 2,5 mg/mL, 5 mg/mL dan 10 mg/mL. Suspensi Mycobacterium
tuberculosis dituangkan ke seluruh permukaan media diamati pertumbuhannya setelah diinkubasi
selama 21 hari. Hasil penelitian menunjukkan ekstrak etanol kaliks bunga Rosella mengandung
minyak atsiri, minyak lemak, tannin, gula pereduksi, flavonoid, kumarin, triterpenoid, dan antosianin.
Ekstrak etanol 70% kaliks bunga Rosella (Hibiscus sabdariffa L.) pada konsentrasi 10% memiliki
efek antibakteri terhadap Mycobacterium tuberculosisdengan menghambat pertumbuhan
Mycobacterium tuberculosis mulai dari mingu pertama sampai mnggu ketiga pengamatan.
Alt. Description
The red Rosella (Hibiscus sabdariffa L.) is medicinal plant that empirically has been used as an
antituberculous drug. Rosella�s calix contains anthocyanins and other nutrients such as calcium,
niacin, riboflavin and iron. This study was conducted experimentally starting with the making of
Rosella flower extract by maceration method followed by examination of chemical content of extract.
The antibacterial effect was performed by in-vitro method using 6 treatment groups, the negative
control group, containing media and aquadest, the ethanol control group, containing media and 70%
ethanol, the positive control group, containing media and isoniazid, and three groups of extracts each
containing media and extracts with a concentration of 2.5 mg / mL , 5 mg / mL and 10 mg / mL.
Mycobacterium tuberculosissuspension was shed over the entire surface and thenthe growth of
Mycobacterium tuberculosis was observed after incubated for 21 days. The results showed that the
ethanol extract of Rosella flower contain essential oils, fatty oil, tannins, reducing sugars, flavonoids,
coumarins, triterpenoids, and anthocyanins. The 70% ethanol extract of calixs of Rosella flower
(Hibiscus sabdariffa L.) at a concentration of 10mg/mLpossessinhibit the growth of Mycobacterium
tuberculosis from the first week until the third week observation.
Date Create | : | 12/01/2021 | Type | : | Text | Format | : | pdf | Language | : | Indonesian | Identifier | : | UEU-Journal-11_0399 | Collection ID | : | 11_0399 |
Source : Jurnal Archives Pharmacia Volume 1 Nomor 1, Januari 2019
Relation Collection: Fakultas Ilmu-Ilmu Kesehatan
Coverage : Civitas Akademika Universitas Esa Unggul
Rights : @2021 Perpustakaan Universitas Esa Unggul
Publication URL : https://digilib.esaunggul.ac.id/aktifitas-antibakteri-ekstrak-etanol-kaliks-bunga-rosella-merah-hibiscus-sabdariffa-l-terhadap-mycobacterium-tuberculosis-17816.html
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