IN-VITRO AND IN-VIVO SUNSCREEN ACTIVITY OF ACTIVE COMPOUNDS ISOLATED FROM FRUITS OF PHALERIA MARCOCARPHA (SCHEFF.) BOERL

UPT. PERPUSTAKAAN Universitas Esa Unggul Kampus Emas UEU - Jakarta Barat
Phone	:	021-5674223, ext 282
Fax	:
E-mail	:	[email protected]
Website	:	http://library.esaunggul.ac.id
Support (Customer Service) :
[email protected]

Welcome..guys!

Have a problem with your access?
Please, contact our technical support below:

LIVE SUPPORT

Astrid Chrisafi

! ATTENTION !

To facilitate the activation process, please fill out the member application form correctly and completely

Registration activation of our members will process up to max 24 hours (confirm by email). Please wait patiently

Still Confuse?
Please read our User Guide

UEU » Journal » Farmasi
Posted by [email protected] at 15/01/2020 12:44:08 • 874 Views

IN-VITRO AND IN-VIVO SUNSCREEN ACTIVITY OF ACTIVE COMPOUNDS ISOLATED FROM FRUITS OF PHALERIA MARCOCARPHA (SCHEFF.) BOERL

Created by :
Dr. APRILITA RINA YANTI EFF, M.Biomed, Apt ( 215020572 )
Dra. RATIH DYAH PERTIWI, M.Farm, Apt IRVANI RAKHMAWATI, S.Si, M.Si

Subject:	SENYAWA AKTIF PHALERIA MARCOCARPHA
Alt. Subject :	ACTIVE COMPOUND PHALERIA MARCOCARPHA
Keyword:	MAHKOSIDE A PHALERIA MARCOCARPHA

Description:

Objective: Mahkota dewa fruits (Phaleria marcocarpha (Scheff.) Boerl) have been found to contain benzophenone and xanthone derivatives which have a protective effect against ultraviolet light. This study was aimed to evaluate the sunscreen activities of mahkoside A, mangiferin and 6, 4-dihydroxy4-methoxybenzophenone-2-O-β-D-glucopyranoside (6, 4-DHMP) isolated from Mahkota dewa fruits in-vitro and in-vivo. Methods: In-vitro�sunscreen activity was evaluated using spectrophotometric method by measuring percentage transmission of erythema, percentage transmission of pigmentation and sun protection factor (SPF). The sunscreen activity assays in-vivo was conducted by observing the effect of erythema in rats after exposed to an exotera lamp for 24 h. Results: In-vitro assays showed that mah- koside A, mangiferin and 6, 4-dihydroxy-4-methoxybenzophenone-2-O-β-Dglucopyranoside at a concentration of 100 ppm had SPF value of 3.44, 2.82 and 3.08 respectively. In-vivo test results showed that mangiferin at concentrations of 12.5%, 25%, and 50% decreased the amount of erythema and erythema diameter significantly different than negative control (p <0.05). Conclusion: Mahkoside A, mangiferin and 6, 4-DHMP possessed sunscreen activity in-vitro and in-vivo.

Contributor	:	TYAS PUTRI UTAMI, S.Pd, M.Biomed
Date Create	:	15/01/2020
Type	:	Text
Format	:	PDF
Language	:	Indonesian
Identifier	:	UEU-Journal-11_0072
Collection ID	:	11_0072

Source :
J Young Pharm, 2018; 10(2) Suppl: s106-s110

Relation Collection:
Fakultas Ilmu Kesehatan

Coverage :
Civitas Akademika Universitas Esa Unggul

Rights :
@2020 Perpustakaan Universitas Esa Unggul

Publication URL :
https://digilib.esaunggul.ac.id/invitro-and-invivo-sunscreen-activity-of-active-compounds-isolated-from-fruits-of-phaleria-marcocarpha-scheff-boerl-14156.html

[ Free Download - Free for All ]