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UEU » Journal » Fisioterapi Posted by [email protected] at 07/02/2020 16:33:29 • 450 Views
PERANAN GEN CD40 DAN CD40L (CD154) DALAM
PENINGKATAN EKSPRESI SEL TIROIDCreated by :
Trisia Lusiana Amir ( 0308089002 )
Subject: | GEN TIROID | Alt. Subject : | GEN THYROID | Keyword: | POLYMORPHISM THYROID |
Description:
CD40 merupakan salah satu anggota TNFR yang secara umum diekspresikan pada
permukaan sel B. Aktivitasnya dipengaruhi oleh CD40L (CD154) pada sel T
CD4+ yang teraktivasi. Interaksi CD40-CD154 berperan dalam regulasi imun,
terutama memediasi respon sel B yang dipengaruhi sel T. Interaksi CD40-CD154
yang abnormal dapat mengakibatkan terjadinya GD, dengan mempengaruhi
aktivitas sel tiroid. Polimorfisme gen CD40 telah dilaporkan dapat meningkatkan
proses translasi dan ekspresi protein CD40 yang berpengaruh terhadap patogenesis
GD.
Date Create | : | 07/02/2020 | Type | : | Text | Format | : | PDF | Language | : | Indonesian | Identifier | : | UEU-Journal-11_0114 | Collection ID | : | 11_0114 |
Source : Artikel Jurnal
Relation Collection: Fakultas Fisioterapi
Coverage : Civitas Akademika Universitas Esa Unggul
Rights : @2020 Perpustakaan Universitas Esa Unggul
Publication URL : https://digilib.esaunggul.ac.id/peranan-gen-cd40-dan-cd40l-cd154-dalampeningkatan-ekspresi-sel-tiroid-14500.html
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