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UEU » Journal » Fisioterapi
Posted by [email protected] at 07/02/2020 16:33:29  •  451 Views


PERANAN GEN CD40 DAN CD40L (CD154) DALAM PENINGKATAN EKSPRESI SEL TIROID

Created by :
Trisia Lusiana Amir ( 0308089002 )



SubjectGEN
TIROID
Alt. Subject GEN
THYROID
KeywordPOLYMORPHISM
THYROID

Description:

CD40 merupakan salah satu anggota TNFR yang secara umum diekspresikan pada permukaan sel B. Aktivitasnya dipengaruhi oleh CD40L (CD154) pada sel T CD4+ yang teraktivasi. Interaksi CD40-CD154 berperan dalam regulasi imun, terutama memediasi respon sel B yang dipengaruhi sel T. Interaksi CD40-CD154 yang abnormal dapat mengakibatkan terjadinya GD, dengan mempengaruhi aktivitas sel tiroid. Polimorfisme gen CD40 telah dilaporkan dapat meningkatkan proses translasi dan ekspresi protein CD40 yang berpengaruh terhadap patogenesis GD.

Date Create:07/02/2020
Type:Text
Format:PDF
Language:Indonesian
Identifier:UEU-Journal-11_0114
Collection ID:11_0114


Source :
Artikel Jurnal

Relation Collection:
Fakultas Fisioterapi

Coverage :
Civitas Akademika Universitas Esa Unggul

Rights :
@2020 Perpustakaan Universitas Esa Unggul


Publication URL :
https://digilib.esaunggul.ac.id/peranan-gen-cd40-dan-cd40l-cd154-dalampeningkatan-ekspresi-sel-tiroid-14500.html




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